https://www.acmrjournal.com/index.php/ACMR/issue/feedAdvances in Clinical Medical Research2025-11-20T04:16:21+00:00Editor, ACMReditor.chief.acmr@gmail.comOpen Journal Systems<p style="text-align: justify;"><img src="https://www.acmrjournal.com/archive/wp-content/uploads/2023/04/cover_issue_9_en_US-scaled-e1682543908435.jpg" alt="" width="311" height="440" />The Advances in Clinical Medical Research (ACMR) Journal was started in 2018 with the aim to provide the recent trends in biomedical arena. The Advances in Clinical Medical Research is an online and print peer-reviewed journal which welcomes papers dealing with all aspects of medical and surgical specialties. Advances in Clinical Medical Research publishes high quality research and reviews and aims to ensure that the results of all well-conducted research are published, regardless of their outcome.</p> <p style="text-align: justify;">ACMR publishes a wide variety of research in preclinical and clinical area of global interest across all medical disciplines, enabling clinicians and other researchers to learn about developments and innovations within these disciplines and across the boundaries between disciplines. The journal publishes 4 issues per year (Quarterly). Original research articles, brief communications, review articles, case report/series or letter to editor may be submitted.</p>https://www.acmrjournal.com/index.php/ACMR/article/view/94An Integrated Approach to the Rational Use of Medicines: Understanding Adverse Drug Reactions, Drug–drug, and Drug–food Interactions in Clinical Practice2025-11-20T04:16:21+00:00Tanaya Chongderaijournals@gmail.comMr Sagnik Chowdhuryaijournals@gmail.comDr. Suhena Sarkaraijournals@gmail.comDr Birupaksha Biswasaijournals@gmail.com<p>Rational pharmacotherapy remains a central pillar of patient safety and effective healthcare delivery. Yet irrational medicine use and preventable adverse events continue to threaten therapeutic outcomes worldwide. This comprehensive review integrates the concepts of adverse drug reactions (ADRs), drug–drug interactions (DDIs), and drug–food interactions (DFIs) within the broader framework of the rational use of medicines. Drawing on global evidence and regulatory guidance from 2000 to 2025, it analyses the mechanisms, classification, and public-health impact of ADRs; outlines pharmacokinetic and pharmacodynamic principles underlying DDIs and DFIs; and highlights pharmacist-led interventions that promote rational prescribing and pharmacovigilance. The review emphasizes that minimizing ADRs and interactions are inseparable from rational use strategies – encompassing evidence-based prescribing, patient education, and multidisciplinary collaboration. By synthesizing pharmacological science with clinical practice, this paper proposes an integrated model for safer, more rational pharmacotherapy across care settings.</p>2025-11-20T00:00:00+00:00Copyright (c) 2025 Author