A Cross-Sectional Study Comparing Adenosine Deaminase Levels in Pleural Effusion of Tuberculous versus Non-Tuberculous Aetiology
DOI:
https://doi.org/10.48112/acmr.v1i1.7Keywords:
Tuberculosis, A.D.A., L.D.HAbstract
Abstract Views: 51
Tuberculous pleural effusion (TPE) is a common condition in developing countries compared to developed countries. It is one of the most prominent characteristics of extrapulmonary tuberculosis. The enzyme Adenosine deaminase (A.D.A.) is highly active in diseases that induce cellular immunity. Therefore, the present study was designed to evaluate the accuracy of A.D.A. levels in diagnosing pleural effusion caused by tubercular etiology. The study was a cross-sectional type and was conducted at the tertiary care institute from July 2019 to March 2020. A total of one hundred thirty-five patients with pleural effusion were recruited for the study. Among which eighty-nine pleural effusion patients were suffering from tuberculosis, and forty-six pleural effusion patients were without tuberculosis. A p-value < 0.05 was taken as statistically significant. For calculations, IBM SPSS Statistics 21 manufactured by I.B.M., U.S.A was used. Findings of the present study have shown a significant difference between A.D.A. levels of tubercular effusion patients (69.3±27.22) compared to non-tubercular pleural effusion patients (20.46±7.34). Further, there was a significant difference between Lactate dehydrogenase (L.D.H.) levels of the tubercular effusion patients (172.72±25.7) in comparison to non-tubercular pleural effusion patients (81.91±6356). However, there was no significant difference between total protein (p>0.05), glucose level (p>0.05) and total cells (p>0.05) level of both the groups. From this study, it was inferred that the A.D.A. level was considerably high in pleural effusion patients with tubercular aetiology in comparison to non-tubercular pleural effusion.
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